Molecular Details
DICL_CP_0455453
- azane;ruthenium(2+);hexachloride;dihydrate
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0455453
PubChem CID
Molecular Formula
H46Cl6N14O2Ru3 Molecular Weight
790.392 g/mol
Synonyms/Alias
[Azane;ruthenium(2+);hexachloride;dihydrate; Ruthenium Red (Technical Grade); SR-01000076250; RUTHENIUMRED; Ruthenium Red; Technical grade; AKOS024456597; E76380; J-002508; SR-01000076250-2; SR-010000...
InChI Key
JQJSTVUROJELSR-UHFFFAOYSA-H
InChI
InChI=1S/6ClH.14H3N.2H2O.3Ru/h6*1H;14*1H3;2*1H2;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6
IUPAC Name
azane;ruthenium(2+);hexachloride;dihydrate
CAS Number
N/A (Not available)
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
25 0 0 0 0 0 0 0 0 0999 V2000
0.0000 0.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
1.0000 0.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
0.0000 1...
Experimental Data
Activity Data
Target Ion Channel
epithelial calcium channel (ECaC1)
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
IC50: 111 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
Extracellular solution pH 7.4/Intracellular solution pH 7.2
Holding Potential
−100 mV mV
Temperature
20−22 °C
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
25
Rotatable Bonds
0
logP
-17.3649
Complexity
77.537
TPSA (Ų)
553
H-Bond Donors
14
H-Bond Acceptors
14
Ring Count
0